ASSESSMENT OF THE POTENTIAL FOR ISOCYANIC ACID AND OTHER MONOISOCYANATES TO CAUSE RESPIRATORY IRRITATION AND SENSITISATION Uses, occurrence, and occupational exposure to monoisocyanates
ثبت نشده
چکیده
The primary use of methyl isocyanate (MIC, CAS no. 624-83-9) is as a chemical intermediate in the production of carbamate pesticides. MIC is also used to produce polyurethane foam and plastics (ATSDR, 2002). Isocyanic acid (ICA, Cas no. 75-138) does not have commercial uses because of its instability. The potential for occupational exposure to ICA largely arises when it is generated as a thermal degradation product of other industrial processes. Ethyl isocyanate is a liquid used commercially to make pharmaceuticals and pesticides (NJDHSS, 2000). Phenyl isocyanate (PIC, CAS no. 103-71-9) is a trace constituent in commercial diphenyl methane diisocyanate products.
منابع مشابه
Recurrent anaphylaxis to synthetic folic acid.
Food fortifi cation with synthetic folic acid (pteroyl monoglutamic acid) remains a source of debate in terms of benefi t versus issues of safety and consumer choice. Several countries have adopted mandatory folic acid fortifi cation. A decision to proceed in Australasia was made in June, 2007. We report the case of a woman who had three episodes of type I hypersensitivity, including ana phylax...
متن کاملGains from diversification on convex combinations: A majorization and stochastic dominance approach
By incorporating both majorization theory and stochastic dominance theory, this paper presents a general theory and a unifying framework for determining the diversification preferences of risk-averse investors and conditions under which they would unanimously judge a particular asset to be superior. In particular, we develop a theory for comparing the preferences of different convex combination...
متن کاملImproved immunogenicity of tetanus toxoid by Brucella abortus S19 LPS adjuvant.
BACKGROUND Adjuvants are used to increase the immunogenicity of new generation vaccines, especially those based on recombinant proteins. Despite immunostimulatory properties, the use of bacterial lipopolysaccharide (LPS) as an adjuvant has been hampered due to its toxicity and pyrogenicity. Brucella abortus LPS is less toxic and has no pyrogenic properties compared to LPS from other gram negati...
متن کاملSteady electrodiffusion in hydrogel-colloid composites: macroscale properties from microscale electrokinetics.
A rigorous microscale electrokinetic model for hydrogel-colloid composites is adopted to compute macroscale profiles of electrolyte concentration, electrostatic potential, and hydrostatic pressure across membranes that separate electrolytes with different concentrations. The membranes are uncharged polymeric hydrogels in which charged spherical colloidal particles are immobilized and randomly d...
متن کاملPerturbative Analysis of Dynamical Localisation
In this paper we extend previous results on convergent perturbative solutions of the Schrödinger equation of a class of periodically timedependent two-level systems. The situation treated here is particularly suited for the investigation of two-level systems exhibiting the phenomenon of (approximate) dynamical localisation. We also present a convergent perturbative expansion for the secular fre...
متن کامل